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Old World Leishmaniasis

Parasitology

Protozoa

  1. Paul A. Bates BA, PhD Senior Lecturer in Medical Parasitology,
  2. R.W. Ashford BSc, PhD, DSc

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0181

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Bates, P. A. and Ashford, R. 2010. Old World Leishmaniasis. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. Liverpool School of Tropical Medicine, Liverpool, UK

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction
  • 2
    Classification
  • 3
    Structure and Life Cycle
  • 4
    Biochemistry, Molecular Biology, and Genetics
  • 5
    Clinical Aspects
  • 6
    Immunology
  • 7
    Pathology
  • 8
    Diagnosis
  • 9
    Epidemiology
  • 10
    Chemotherapy and Treatment
  • 11
    Vaccination
  • 12
    Integrated Control

Keywords:

  • old world leishmaniasis;
  • leishmaniases-group of human diseases afflicting people;
  • five species of Leishmania-L. major, L. tropica, L. aethiopica, L. donovani, and L. infantum;
  • zymodeme-group of strains sharing given pattern of enzyme electrophoretic mobilities;
  • parasites in two morphological forms-‘amastigotes’ and ‘promastigotes’;
  • amastigotes-ovoid, non-motile, intracellular stages;
  • promastigotes-elongated, motile, extracellular stages;
  • lysosomes in cytoplasm together with organelles;
  • promastigote surface protease, lipophosphoglycan and glycosylphosphatidylinositols