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Positive-Strand RNA Virus Replication in Vertebrate Hosts

Virology

General Characteristics of Viruses

  1. Jo Ellen Brunner PhD1,
  2. Bert L. Semler PhD Professor and Chair2

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0215

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Brunner, J. E. and Semler, B. L. 2010. Positive-Strand RNA Virus Replication in Vertebrate Hosts. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    University of California, Instructional Support Group, School of Biological Sciences, Irvine, CA, USA

  2. 2

    University of California, Department of Microbiology and Molecular Genetics, Irvine, CA, USA

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Common Characteristics Across Families
  • 2
    The Intracellular Replicative Cycle
  • 3
    Conclusions

Keywords:

  • positive-strand RNA virus replication in vertebrate hosts;
  • limited coding capacity of small genomes;
  • conservation of amino acid sequences;
  • initiation of intracellular replicative cycle;
  • translation of viral-specific RNAs;
  • flavivirus virions;
  • viral RNA-dependent RNA polymerase;
  • negative-strand RNA synthesis