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Orthomyxoviruses: Influenza

Virology

Specific Viruses and Viral Infections

  1. Nancy J. Cox PhD Chief, Influenza Branch1,
  2. Gabriele Neumann PhD2,
  3. Ruben O. Donis DVM PhD Chief, Molecular Genetics Section, Influenza Branch3,
  4. Yoshihiro Kawaoka DVM PhD Professor and Director4,5

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0238

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Cox, N. J., Neumann, G., Donis, R. O. and Kawaoka, Y. 2010. Orthomyxoviruses: Influenza. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    Centers for Disease Control and Prevention, Division of Viral and Rickettsial Diseases, Atlanta, GA, USA

  2. 2

    University of Wisconsin-Madison, Department of Pathobiological Sciences, School of Veterinary Medicine, Madison, WI, USA

  3. 3

    Centers for Disease Control and Prevention, Division of Viral and Rickettsial Diseases, National Centers for Infectious Diseases, Atlanta, GA, USA

  4. 4

    University of Tokyo, International Research Center for Infectious Diseases; and Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, Tokyo, Japan

  5. 5

    University of Wisconsin-Madison, Department of Pathobiological Sciences, School of Veterinary Medicine, Madison, WI, USA

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction
  • 2
    Classification
  • 3
    Morphology and Structure
  • 4
    Genome Structure and Function
  • 5
    Clinical Manifestations and Pathogenesis
  • 6
    Antigens
  • 7
    Epidemiology
  • 8
    Diagnosis
  • 9
    Control

Keywords:

  • Orthomyxoviruses causing influenza and recurrent seasonal epidemics;
  • influenza virus replication and evolution-showing epidemiological success of viruses;
  • seroarcheology-testing of sera from older adults for influenza virus antibodies;
  • virion morphogenesis and budding;
  • fusion of influenza viruses to endosomal membrane-mediated by HA;
  • host-cell-mediated selection of antigenic variants;
  • molecular methods for influenza virus infection diagnosis;
  • antigenic drift and its impact