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Prions of Humans and Animals

Virology

Specific Viruses and Viral Infections

  1. Adriano Aguzzi MD PhD hcFRCP FRCPath

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0267

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Aguzzi, A. 2010. Prions of Humans and Animals. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. University Hospital of Zürich, Institute of Neuropathology, Zürich, Switzerland

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Properties of Prions
  • 2
    The Function of the Cellular Prion Protein
  • 3
    The Prion Doppelganger
  • 4
    Clinical and Pathological Aspects of Prion Diseases
  • 5
    Brain Damage in Prion Diseases
  • 6
    Peripheral Prion Pathogenesis
  • 7
    Lymphocytes and Prion Pathogenesis
  • 8
    Prion Hideouts in Lymphoid Organs
  • 9
    The Cellular Basis of Prion Lymphotropism
  • 10
    Sympathetic Nerves: A Neuroimmune Link?
  • 11
    Innate Immunity and Antiprion Defense
  • 12
    Adaptive Immunity and Pre-Exposure Prophylaxis against Prions
  • 13
    Progress in the Diagnosis of Prion Diseases
  • 14
    Perspectives in Prion Immunology
  • 15
    Concluding Remarks
  • 16
    Glossary of Prion Terminology
  • 17
    Acknowledgments

Keywords:

  • prions of humans and animals;
  • transmissible spongiform encephalopathies (TSE);
  • sporadic CJD (sCJD);
  • Gerstmann–Sträussler–Scheinker (GSS) disease;
  • bovine spongiform encephalopathy (BSE);
  • chronic wasting disease (CWD);
  • meat and bone meal (MBM);
  • PrP amyloid