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Antiviral Chemotherapy

Virology

Principles of Diagnosis and Control

  1. Hugh J. Field ScD FRCPath Reader in Comparative Virology1,
  2. Richard J. Whitley MD Professor of Pediatrics, Microbiology, Medicine and Neurosurgery2

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0275

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Field, H. J. and Whitley, R. J. 2010. Antiviral Chemotherapy. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    University of Cambridge, Centre for Veterinary Science, Cambridge, UK

  2. 2

    University of Alabama at Birmingham, Children's Hospital, Birmingham, AL, USA

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction
  • 2
    Discovery and Assessment of New Antiviral Compounds
  • 3
    Mechanism of Action of Important Antiviral Compounds
  • 4
    Problems in Antiviral Chemotherapy
  • 5
    Combination Chemotherapy for Viral Infections
  • 6
    Conclusions and Future Prospects

Keywords:

  • antiviral chemotherapy;
  • thymidine kinase (TK);
  • varicella-zoster virus (VZV);
  • nonnucleoside reverse transcriptase inhibitors (NNRTI);
  • human cytomegalovirus (HCMV);
  • structure–activity relationship (SAR);
  • ganciclovir (GCV);
  • penciclovir (PCV)