Chapter 1. Principles of Brain Function and Structure: 1 Genetics, Physiology and Chemistry

  1. Michael R. Trimble MD, FRCP, FRCPsych Professor of Behavioural Neurology1 and
  2. Mark S. George MD Distinguished Professor of Psychiatry Director MUSC Director2,3,4,5,6

Published Online: 21 JUL 2010

DOI: 10.1002/9780470689394.ch1

Biological Psychiatry, Third Edition

Biological Psychiatry, Third Edition

How to Cite

Trimble, M. R. and George, M. S. (2010) Principles of Brain Function and Structure: 1 Genetics, Physiology and Chemistry, in Biological Psychiatry, Third Edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470689394.ch1

Author Information

  1. 1

    Institute of Neurology, Queen Square, London UK

  2. 2

    Radiology and Neurosciences, Medical University of South Carolina, USA

  3. 3

    Brain Stimulation Laboratory, Medical University of South Carolina, USA

  4. 4

    Center for Advanced Imaging Research (CAIR), Medical University of South Carolina, USA

  5. 5

    SC Brain Imaging Center of Excellence, Medical University of South Carolina, USA

  6. 6

    Ralph H. Johnson VA Medical Center, Charleston, SC, USA

Publication History

  1. Published Online: 21 JUL 2010
  2. Published Print: 27 AUG 2010

ISBN Information

Print ISBN: 9780470688946

Online ISBN: 9780470689394

SEARCH

Keywords:

  • brain function and structure principles - 1 genetics, physiology and chemistry;
  • limbic system and closely connected structures;
  • neuroanatomy and brain neurochemistry - for those studying biological psychiatry;
  • DNA replication and transcription;
  • genetic programme - determined by DNA;
  • complimentary cDNA probes - produced using mRNA as template with enzyme reverse transcriptase;
  • Receptors for Excitatory Amino Acids (EAA);
  • brain chemistry and metabolism;
  • glucose and glycogen catabolism and production of ATP - via well-known tricarboxylic acid (Krebs) cycle;
  • interrelationships among transmitters

Summary

This chapter contains sections titled:

  • Introduction

  • Genetics

  • Brain chemistry and metabolism

  • The metabolism of glucose

  • Proteins and fatty acids

  • Cell membranes

  • Synapses

  • Receptors

  • Neurones

  • Neurotransmitters

  • Interrelationships among transmitters

  • Transmitter dispersal

  • CNS inflammation