Chapter 2. Principles of Brain Function and Structure: 2 Anatomy

  1. Michael R. Trimble MD, FRCP, FRCPsych Professor of Behavioural Neurology1 and
  2. Mark S. George MD Distinguished Professor of Psychiatry Director MUSC Director2,3,4,5,6

Published Online: 21 JUL 2010

DOI: 10.1002/9780470689394.ch2

Biological Psychiatry, Third Edition

Biological Psychiatry, Third Edition

How to Cite

Trimble, M. R. and George, M. S. (2010) Principles of Brain Function and Structure: 2 Anatomy, in Biological Psychiatry, Third Edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470689394.ch2

Author Information

  1. 1

    Institute of Neurology, Queen Square, London UK

  2. 2

    Radiology and Neurosciences, Medical University of South Carolina, USA

  3. 3

    Brain Stimulation Laboratory, Medical University of South Carolina, USA

  4. 4

    Center for Advanced Imaging Research (CAIR), Medical University of South Carolina, USA

  5. 5

    SC Brain Imaging Center of Excellence, Medical University of South Carolina, USA

  6. 6

    Ralph H. Johnson VA Medical Center, Charleston, SC, USA

Publication History

  1. Published Online: 21 JUL 2010
  2. Published Print: 27 AUG 2010

ISBN Information

Print ISBN: 9780470688946

Online ISBN: 9780470689394

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Keywords:

  • brain function and structure principles and anatomy;
  • brain areas - importance to biological psychiatry;
  • parallel distributed processing (PDP);
  • neuroanatomy of emotion;
  • basic anatomy of cortico-striato-thalamic re-entrant loops;
  • GABA, important inhibitory transmitter in amygdala;
  • ‘fast’ and ‘slower’ routes - to amygdala in response to a frightening stimulus;
  • classical comparisons of sympathetic and parasympathetic divisions of ANS;
  • ascending and descending limbic-system connections;
  • connections underpinning - concept of basal forebrain macrosystems

Summary

This chapter contains sections titled:

  • Introduction

  • The neuroanatomy of emotion

  • Individual anatomical structures

  • Ascending and descending limbic-system connections

  • Macrosystems

  • The basal ganglia and the re-entrant circuits

  • The ventral striatum and ‘limbic striatum’

  • The ascending cholinergic systems

  • Cortical regions of interest

  • The cerebellum