Chapter 3. Bias in Randomized Controlled Trials

  1. Alejandro R. Jadad MD, DPhil, FRCPC1,2,
  2. Murray W. Enkin MD, FRCSC, FACOG, DSc (hon), LLD (hon)3,4

Published Online: 15 APR 2008

DOI: 10.1002/9780470691922.ch3

Book Title

Randomized Controlled Trials: Questions, Answers, and Musings, Second Edition

Randomized Controlled Trials: Questions, Answers, and Musings, Second Edition

Additional Information

How to Cite

Jadad, A. R. and Enkin, M. W. (2008) Bias in Randomized Controlled Trials, in Randomized Controlled Trials: Questions, Answers, and Musings, Second Edition, Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470691922.ch3

Author Information

  1. 1

    Chief Innovator and Founder, Centre for Global eHealth Innovation, Canada Research Chair in eHealth Innovation, Rose Family Chair in Supportive Care

  2. 2

    Professor, Departments of Health Policy, Management and Evaluation; Public Health Sciences; and Anesthesia, University Health Network and University of Toronto, Toronto, Canada

  3. 3

    Professor Emeritus; Departments of Obstetrics and Gynecology; and Clinical Epidemiology and Biostatistics; McMaster University; Hamilton, Ontario

  4. 4

    Adjunct Professor, University of Toronto, Toronto, Canada

Publication History

  1. Published Online: 15 APR 2008
  2. Published Print: 4 JUN 2007

ISBN Information

Print ISBN: 9781405132664

Online ISBN: 9780470691922

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Keywords:

  • health care;
  • bias;
  • clinicians;
  • surgical interventions;
  • withdrawal bias

Summary

This chapter contains section titled:

  • What is bias?

  • Why does bias in an RCT matter?

  • What are the main types of bias in RCTs?

  • Other important sources of bias

  • Musings

  • References

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