Chapter 12. ACE Inhibitors as Immunomodulators: Treatment of Cardiovascular Disease

  1. Ronald Ross Watson1,2 and
  2. Douglas F. Larson3
  1. Christina Grothusen and
  2. Bernhard Schieffer

Published Online: 15 APR 2008

DOI: 10.1002/9780470692325.ch12

Immune Dysfunction and Immunotherapy in Heart Disease

Immune Dysfunction and Immunotherapy in Heart Disease

How to Cite

Grothusen, C. and Schieffer, B. (2007) ACE Inhibitors as Immunomodulators: Treatment of Cardiovascular Disease, in Immune Dysfunction and Immunotherapy in Heart Disease (eds R. R. Watson and D. F. Larson), Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470692325.ch12

Editor Information

  1. 1

    Department of Nutritional Sciences, The University of Arizona; and Sarver Heart Center, College of Medicine, The University of Arizona

  2. 2

    Division of Health Promotion Sciences, Mel and Enid Zuckerman Arizona College of Public Health, The University of Arizona Tucson, AZ USA

  3. 3

    Sarver Heart Center College of Medicine The University of Arizona Tucson, AZ USA

Publication History

  1. Published Online: 15 APR 2008
  2. Published Print: 30 AUG 2007

ISBN Information

Print ISBN: 9781405155687

Online ISBN: 9780470692325

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Keywords:

  • cardiovascular disease;
  • immunomodulators;
  • artherosclerosis;
  • blood flow;
  • cathepsin

Summary

This chapter contains section titled:

  • Introduction

  • RAS components

  • ACE signaling

  • Impact of RAS on immunomodulatory cells in atherosclerosis

  • Detrimental interplay between cytokines and RAS in atherosclerosis

  • ACE signaling and immunomodulation in cardiovascular disease

  • ACE-inhibitors as immunomodulators in cardiovascular disease

  • Summary

  • References