Chapter 8. Immunosuppression in Promotion of Cardiac Allograft Vasculopathy

  1. Ronald Ross Watson1,2 and
  2. Douglas F. Larson3
  1. Farzad Moien-Afshari,
  2. Jonathan Choy,
  3. Bruce M. McManus and
  4. Ismail Laher

Published Online: 15 APR 2008

DOI: 10.1002/9780470692325.ch8

Immune Dysfunction and Immunotherapy in Heart Disease

Immune Dysfunction and Immunotherapy in Heart Disease

How to Cite

Moien-Afshari, F., Choy, J., McManus, B. M. and Laher, I. (2007) Immunosuppression in Promotion of Cardiac Allograft Vasculopathy, in Immune Dysfunction and Immunotherapy in Heart Disease (eds R. R. Watson and D. F. Larson), Blackwell Publishing Ltd, Oxford, UK. doi: 10.1002/9780470692325.ch8

Editor Information

  1. 1

    Department of Nutritional Sciences, The University of Arizona; and Sarver Heart Center, College of Medicine, The University of Arizona

  2. 2

    Division of Health Promotion Sciences, Mel and Enid Zuckerman Arizona College of Public Health, The University of Arizona Tucson, AZ USA

  3. 3

    Sarver Heart Center College of Medicine The University of Arizona Tucson, AZ USA

Publication History

  1. Published Online: 15 APR 2008
  2. Published Print: 30 AUG 2007

ISBN Information

Print ISBN: 9781405155687

Online ISBN: 9780470692325

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Keywords:

  • immunosuppression;
  • cardiac allograft;
  • vasculopathy;
  • graft failure;
  • aretrial function

Summary

This chapter contains section titled:

  • Introduction

  • Cardiac allograft vasculopathy

  • Cyclosporine A

  • Endothelium-dependent and endothelium-independent relaxation in septal coronary arteries of transplanted hearts: a progressive dysfunction without treatment

  • Smooth muscle cell function in septal coronary arteries of transplanted hearts: a progressive dysfunction without treatment

  • Myogenic tone in transplant arteries

  • Effect of CsA treatment on allograft coronary artery myogenic tone

  • Conclusions

  • Acknowledgments

  • References