Chapter 16. Effect Measures for Meta‒Analysis of Trials with Binary Outcomes

  1. Matthias Egger1,
  2. George Davey Smith2 and
  3. Douglas G Altman3
  1. Jonathan J Deeks and
  2. Douglas G Altman

Published Online: 17 MAR 2008

DOI: 10.1002/9780470693926.ch16

Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition

Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition

How to Cite

Deeks, J. J. and Altman, D. G. (2001) Effect Measures for Meta‒Analysis of Trials with Binary Outcomes, in Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition (eds M. Egger, G. D. Smith and D. G. Altman), BMJ Publishing Group, London, UK. doi: 10.1002/9780470693926.ch16

Editor Information

  1. 1

    Senior Lecturer in Epidemiology and Public Health Medicine, Division of Health Services, Research and MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK

  2. 2

    Professor of Clinical Epidemiology, Division of Epidemiology and MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK

  3. 3

    Professor of Statistics in Medicine, ICRF Medical Statistics, Group, Centre for Statistics in Medicine, Institute of Health Sciences, University of Oxford, UK

Publication History

  1. Published Online: 17 MAR 2008
  2. Published Print: 1 JAN 2001

ISBN Information

Print ISBN: 9780727914880

Online ISBN: 9780470693926

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Keywords:

  • effect measures;
  • meta-analysis;
  • binary outcomes;
  • meta-analytical summary;
  • risk difference

Summary

This chapter contains section titled:

  • Summary Points

  • Criteria for Selection of a Summary Statistic

  • Odds and Risks

  • Measure of Absolute Effect—the Risk Difference

  • Measures of Relative Effect—the Risk Ratio and Odds Ratio

  • What is the Event?

  • The L'Abbé plot

  • Empirical Evidence of Consistency

  • Empirical Evidence of Ease of Interpretation

  • Case Studies

  • Discussion

  • Acknowledgements