Chapter 6. Obtaining Individual Patient Data from Randomised Controlled Trials

  1. Matthias Egger1,
  2. George Davey Smith2 and
  3. Douglas G Altman3
  1. Michael J Clarke and
  2. Lesley A Stewart

Published Online: 17 MAR 2008

DOI: 10.1002/9780470693926.ch6

Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition

Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition

How to Cite

Clarke, M. J. and Stewart, L. A. (2001) Obtaining Individual Patient Data from Randomised Controlled Trials, in Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition (eds M. Egger, G. D. Smith and D. G. Altman), BMJ Publishing Group, London, UK. doi: 10.1002/9780470693926.ch6

Editor Information

  1. 1

    Senior Lecturer in Epidemiology and Public Health Medicine, Division of Health Services, Research and MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK

  2. 2

    Professor of Clinical Epidemiology, Division of Epidemiology and MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK

  3. 3

    Professor of Statistics in Medicine, ICRF Medical Statistics, Group, Centre for Statistics in Medicine, Institute of Health Sciences, University of Oxford, UK

Publication History

  1. Published Online: 17 MAR 2008
  2. Published Print: 1 JAN 2001

ISBN Information

Print ISBN: 9780727914880

Online ISBN: 9780470693926

SEARCH

Keywords:

  • patient data;
  • randomised controlled trials;
  • health care;
  • public health;
  • systematic reviews

Summary

This chapter contains section titled:

  • Summary Points

  • What are Individual Patient Data Reviews?

  • Improved Follow—Up

  • Time—to—Event Analyses

  • Estimating Time—to—Event Outcomes from Published Information

  • Effects in Patient Subgroups and on Different Outcomes

  • How to Obtain Data that are as Complete as Possible

  • What if IPD are not Available?

  • Potential Disadvantages of IPD Reviews

  • Examples of how the Collection of IPD can make a Difference to the Findings of a Review

  • Conclusion