Chapter 8. Going Beyond the Grand Mean: Subgroup Analysis in Meta-Analysis of Randomised Trials

  1. Matthias Egger1,
  2. George Davey Smith2 and
  3. Douglas G Altman3
  1. George Davey Smith and
  2. Matthias Egger

Published Online: 17 MAR 2008

DOI: 10.1002/9780470693926.ch8

Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition

Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition

How to Cite

Smith, G. D. and Egger, M. (2001) Going Beyond the Grand Mean: Subgroup Analysis in Meta-Analysis of Randomised Trials, in Systematic Reviews in Health Care: Meta-Analysis in Context, Second Edition (eds M. Egger, G. D. Smith and D. G. Altman), BMJ Publishing Group, London, UK. doi: 10.1002/9780470693926.ch8

Editor Information

  1. 1

    Senior Lecturer in Epidemiology and Public Health Medicine, Division of Health Services, Research and MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK

  2. 2

    Professor of Clinical Epidemiology, Division of Epidemiology and MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK

  3. 3

    Professor of Statistics in Medicine, ICRF Medical Statistics, Group, Centre for Statistics in Medicine, Institute of Health Sciences, University of Oxford, UK

Publication History

  1. Published Online: 17 MAR 2008
  2. Published Print: 1 JAN 2001

ISBN Information

Print ISBN: 9780727914880

Online ISBN: 9780470693926

SEARCH

Keywords:

  • subgroup analysis;
  • meta-analysis;
  • randomised trials;
  • meta-analytic subgroup;
  • patient data

Summary

This chapter contains section titled:

  • Summary Points

  • Subgroup Analysis

  • Meta—Regression: Examining Gradients in Treatment Effects

  • Risk Stratification in Meta—Analysis

  • Problems in Risk Stratification

  • Use of Risk Indicators in Meta—Analysis

  • Confounding

  • Acknowledgements