Chapter 92. Airway Smooth Muscle Dysfunction in Asthma

  1. William W. Busse MD1 and
  2. Stephen T. Holgate BSc, MD, FRCP2
  1. R. Robert Schellenberg

Published Online: 16 APR 2008

DOI: 10.1002/9780470694923.ch22

Asthma and Rhinitis, Second Edition

Asthma and Rhinitis, Second Edition

How to Cite

Schellenberg, R. R. (2000) Airway Smooth Muscle Dysfunction in Asthma, in Asthma and Rhinitis, Second Edition (eds W. W. Busse and S. T. Holgate), Blackwell Science Ltd, Oxford, UK. doi: 10.1002/9780470694923.ch22

Editor Information

  1. 1

    Professor of Medicine Head, Clinical Immunology, University of Wisconsin-Madison Medical School, Department of Medicine, Madison Wisconsin, USA

  2. 2

    Clinical Professor of Immuno-Pharmacology, Medical Specialties, Southampton General Hospital, Youthampton, UK

Publication History

  1. Published Online: 16 APR 2008
  2. Published Print: 1 JAN 2000

ISBN Information

Print ISBN: 9780632041756

Online ISBN: 9780470694923

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Keywords:

  • airway smooth muscle;
  • asthma;
  • myofibroblasts;
  • leukotrienes;
  • isometric force generation

Summary

This chapter contains section titled:

  • Excessive Airway Narrowing

  • Pathological Changes in Asthma Affecting Airway Smooth Muscle

  • Mechanics of Human Airway Smooth Muscle

  • Experimentally Increased Shortening of Airway Smooth Muscle

  • Proliferation of Airway Smooth Muscle in Asthma-Fact or Artefact?

  • Human Asthmatic Smooth-Muscle Responses

  • Conclusion

  • References