Chapter 102. Glucocorticoids in Asthma and Rhinitis

  1. William W. Busse MD1 and
  2. Stephen T. Holgate BSc, MD, FRCP2
  1. Alan K. Kamada and
  2. Stanley J. Szefler

Published Online: 16 APR 2008

DOI: 10.1002/9780470694923.ch32

Asthma and Rhinitis, Second Edition

Asthma and Rhinitis, Second Edition

How to Cite

Kamada, A. K. and Szefler, S. J. (2000) Glucocorticoids in Asthma and Rhinitis, in Asthma and Rhinitis, Second Edition (eds W. W. Busse and S. T. Holgate), Blackwell Science Ltd, Oxford, UK. doi: 10.1002/9780470694923.ch32

Editor Information

  1. 1

    Professor of Medicine Head, Clinical Immunology, University of Wisconsin-Madison Medical School, Department of Medicine, Madison Wisconsin, USA

  2. 2

    Clinical Professor of Immuno-Pharmacology, Medical Specialties, Southampton General Hospital, Youthampton, UK

Publication History

  1. Published Online: 16 APR 2008
  2. Published Print: 1 JAN 2000

ISBN Information

Print ISBN: 9780632041756

Online ISBN: 9780470694923



  • glucocorticoids;
  • rhinitis;
  • asthma;
  • chemotaxis;
  • hydrocortisone


This chapter contains section titled:

  • Introduction

  • Chemistry and Structure-Activity Relationships

  • The Glucocorticoid Receptor

  • Molecular Mechanisms of Glucocorticoids

  • Cellular Mechanisms of Glucocorticoids

  • Effects on Cell Trafficking and Chemotaxis

  • Effects on Mediator Synthesis and Release

  • Effects on Vascular Permeability

  • Effects on P-Adrenergic Receptor Activity

  • Effects on Bronchial Hyperreactivity

  • Pharmacokinetics

  • Pharmacodynamics

  • Summary

  • References