Chapter 2. Vascular Biology and Atherogenesis

  1. Peter P. Toth M.D., PH.D. Director of Preventive Cardiology Chief of Medicine Clinical Associate Professor1,2,3,4 and
  2. Kevin C. Maki PH.D. President Chief Science Officer5

Published Online: 1 OCT 2008

DOI: 10.1002/9780470696873.ch2

Practical Lipid Management: Concepts and Controversies

Practical Lipid Management: Concepts and Controversies

How to Cite

Toth, P. P. and Maki, K. C. (2008) Vascular Biology and Atherogenesis , in Practical Lipid Management: Concepts and Controversies, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470696873.ch2

Author Information

  1. 1

    Sterling Rock Falls Clinic, Ltd., USA

  2. 2

    CGH Medical Center Sterling, Illinois, USA

  3. 3

    Departments of Family and Community Medicine, University of Illinois College of Medicine Peoria, Illinois, USA

  4. 4

    Southern Illinois University School of Medicine, Springfield, Illinois, USA

  5. 5

    Provident Clinical Research & Consulting, Inc., Glen Ellyn, Illinois and Bloomington, Indiana, USA

Publication History

  1. Published Online: 1 OCT 2008
  2. Published Print: 17 OCT 2008

ISBN Information

Print ISBN: 9780470056905

Online ISBN: 9780470696873



  • vascular biology and atherogenesis;
  • atherosclerosis and atherosclerotic disease;
  • endothelial continuity and barrier function;
  • angiotensin converting enzyme (ACE);
  • macrophage colony stimulating factor (M-CSF);
  • atheromatous plaques;
  • ST-segment elevating MI (ST-segment elevating myocardial infarction (STEMI));
  • atheromatous plaque thrombosis and intraplaque hemorrhage


This chapter contains sections titled:

  • Introduction

  • Arterial Structure

  • Endothelial Cell Function and Dysfunction

  • The Role of Monocytes and Lymphocytes

  • Atheromatous Plaques