Chapter 16. Gene Therapy

  1. Sotiris Missailidis
  1. Maria Belimezi,
  2. Teni Boulikas and
  3. Michael L. Roberts

Published Online: 7 NOV 2008

DOI: 10.1002/9780470697047.ch16

Anticancer Therapeutics

Anticancer Therapeutics

How to Cite

Belimezi, M., Boulikas, T. and Roberts, M. L. (2008) Gene Therapy, in Anticancer Therapeutics (ed S. Missailidis), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470697047.ch16

Editor Information

  1. Department of Chemistry and Analytical Sciences, The Open University, Milton Keynes, UK

Author Information

  1. Regulon Inc. (USA), Afxentiou 7, Alimos, Athens, Greece

Publication History

  1. Published Online: 7 NOV 2008
  2. Published Print: 21 NOV 2008

ISBN Information

Print ISBN: 9780470723036

Online ISBN: 9780470697047



  • gene therapy concept;
  • cancer gene therapy retroviruses;
  • recombinant retroviruses;
  • cancer gene therapy adenoviruses;
  • cancer gene therapy and tumour suppressor genes;
  • IL-12 gene therapy;
  • therapeutic oncolytic viruses;
  • oncolytic measles virus expressing an enhanced green fluorescent protein (MV-eGFP)


This chapter contains sections titled:

  • The Concept of Gene Therapy

  • Steps for Successful Gene Therapy

  • Retroviruses in Cancer Gene Therapy

  • Adenoviruses in Cancer Gene Therapy

  • Gene Therapy of Cancer

  • Cancer Immunotherapy with Cytokine Genes

  • IL-12 in Cancer Immunotherapy

  • Viruses able to Kill Cancer Cells

  • References