Chapter 2. Combinatorial Approaches to Anticancer Drug Design

  1. Sotiris Missailidis
  1. Sotiris Missailidis

Published Online: 7 NOV 2008

DOI: 10.1002/9780470697047.ch2

Book Title

Anticancer Therapeutics

Anticancer Therapeutics

Additional Information

How to Cite

Missailidis, S. (2008) Combinatorial Approaches to Anticancer Drug Design, in Anticancer Therapeutics (ed S. Missailidis), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470697047.ch2

Editor Information

  1. Department of Chemistry and Analytical Sciences, The Open University, Milton Keynes, UK

Author Information

  1. Department of Chemistry and Analytical Sciences, The Open University, Milton Keynes, UK

Publication History

  1. Published Online: 7 NOV 2008
  2. Published Print: 21 NOV 2008

ISBN Information

Print ISBN: 9780470723036

Online ISBN: 9780470697047

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CHAPTER TOOLS

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Keywords:

  • small molecule drug design combinatorial approach;
  • anticancer drug design and combinatorial approaches;
  • building block selection and actual library synthesis;
  • phage display technology;
  • peptide libraries synthetic approaches;
  • aptamer selection;
  • Systematic Evolution of Ligands by Exponential Enrichment (SELEX);
  • ‘non-SELEX’-based methods

Summary

This chapter contains sections titled:

  • Introduction

  • Combinatorial Approaches for Small Molecule Drug Design

  • Display Technologies

  • Aptamer Selection

  • Conclusions

  • References

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