Chapter 20. Clinical Trials in Oncology

  1. Sotiris Missailidis
  1. Tim Friede,
  2. Janet Dunn and
  3. Nigel Stallard

Published Online: 7 NOV 2008

DOI: 10.1002/9780470697047.ch20

Anticancer Therapeutics

Anticancer Therapeutics

How to Cite

Friede, T., Dunn, J. and Stallard, N. (2008) Clinical Trials in Oncology, in Anticancer Therapeutics (ed S. Missailidis), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470697047.ch20

Editor Information

  1. Department of Chemistry and Analytical Sciences, The Open University, Milton Keynes, UK

Author Information

  1. Warwick Medical School, The University of Warwick, Warwick, UK

Publication History

  1. Published Online: 7 NOV 2008
  2. Published Print: 21 NOV 2008

ISBN Information

Print ISBN: 9780470723036

Online ISBN: 9780470697047



  • oncology clinical trials;
  • simple randomization;
  • World Medical Association (WMA) - Declaration of Helsinki;
  • cytotoxic anticancer agents;
  • early-phase oncology clinical trials;
  • continual reassessment method (CRM);
  • systematic literature review and clinical trial;
  • pharmacovigilence monitoring and Investigational Medicinal Product (IMP) trial


This chapter contains sections titled:

  • Clinical Trials

  • Early-Phase (Phase I and Phase II) Clinical Trials in Oncology

  • Confirmatory (Phase III) Trials in Oncology

  • Further Issues in Clinical Trials in Oncology