Chapter 8. Antitumour Antibiotics

  1. Sotiris Missailidis
  1. Manuel M. Paz

Published Online: 7 NOV 2008

DOI: 10.1002/9780470697047.ch8

Anticancer Therapeutics

Anticancer Therapeutics

How to Cite

Paz, M. M. (2008) Antitumour Antibiotics, in Anticancer Therapeutics (ed S. Missailidis), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470697047.ch8

Editor Information

  1. Department of Chemistry and Analytical Sciences, The Open University, Milton Keynes, UK

Author Information

  1. Department of Organic Chemistry, Faculty of Science, University of Santiago de Compostela, Lugo Campus, Lugo, Spain

Publication History

  1. Published Online: 7 NOV 2008
  2. Published Print: 21 NOV 2008

ISBN Information

Print ISBN: 9780470723036

Online ISBN: 9780470697047

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Keywords:

  • antitumour antibiotics;
  • actinomycins from Actinomyces antibioticus cultures;
  • Hodgkin's and non-Hodgkin's lymphoma Blenoxane treatment;
  • activated bleomycin DNA cleavage;
  • Daunorubicin and Streptomyces cultures;
  • Topoisomerase I - camptothecin biological target;
  • teniposide;
  • myelosuppression - dose related and dose limiting

Summary

This chapter contains sections titled:

  • Introduction

  • Actinomycin

  • Mitomycin C

  • Bleomycin

  • Anthracyclines

  • Trabectedin (Ecteinascidin, ET-743)

  • Camptothecins

  • Podophyllotoxins

  • References