Chapter 11. Escherichia coli Stress Response as a Tool for Detection of Toxicity

  1. Saura C. Sahu
  1. Arindam Mitra1,
  2. Nabarun Chakraborti2 and
  3. Suman Mukhopadhyay3

Published Online: 14 OCT 2008

DOI: 10.1002/9780470699638.ch11

Toxicogenomics: A Powerful Tool for Toxicity Assessment

Toxicogenomics: A Powerful Tool for Toxicity Assessment

How to Cite

Mitra, A., Chakraborti, N. and Mukhopadhyay, S. (2008) Escherichia coli Stress Response as a Tool for Detection of Toxicity, in Toxicogenomics: A Powerful Tool for Toxicity Assessment (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470699638.ch11

Editor Information

  1. Division of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, Laurel, MD 20708, USA

Author Information

  1. 1

    Virginia Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD, USA

  2. 2

    Department of Animal and Avian Sciences, University of Maryland, College Park, MD, USA

  3. 3

    Center for Biosystems Research, University of Maryland Biotechnology Institute, College Park, MD, USA

Publication History

  1. Published Online: 14 OCT 2008
  2. Published Print: 10 OCT 2008

ISBN Information

Print ISBN: 9780470518236

Online ISBN: 9780470699638

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Keywords:

  • toxicogenomics and toxicity evaluation principle;
  • extraintestinal pathogenic Escherichia coli;
  • extraintestinal pathogenic E. coli (ExPEC);
  • signal transduction system - two-component system (TCS);
  • toxicity detection E. coli stress response tool;
  • NetAffix GeneOntology (GO) analysis tool;
  • toxicity-detection studies and E. coli regulatory pathways

Summary

This chapter contains sections titled:

  • Introduction

  • Extraintestinal Pathogenic Escherichia coli

  • Stress Responses

  • Two-component Systems as Signal Transducers

  • Bacterial Biosensors for Detection of Toxicity

  • Global Gene Expression Profiling of the BarA–UvrY TCS

  • Conclusion

  • References