Chapter 19. Potential Uses of Toxicogenomic Biomarkers in Occupational Health and Risk Assessment

  1. Saura C. Sahu
  1. Paul A. Nony

Published Online: 14 OCT 2008

DOI: 10.1002/9780470699638.ch19

Toxicogenomics: A Powerful Tool for Toxicity Assessment

Toxicogenomics: A Powerful Tool for Toxicity Assessment

How to Cite

Nony, P. A. (2008) Potential Uses of Toxicogenomic Biomarkers in Occupational Health and Risk Assessment, in Toxicogenomics: A Powerful Tool for Toxicity Assessment (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470699638.ch19

Editor Information

  1. Division of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, Laurel, MD 20708, USA

Author Information

  1. Center for Toxicology and Environmental Health, LLC, North Little Rock, AR, USA

Publication History

  1. Published Online: 14 OCT 2008
  2. Published Print: 10 OCT 2008

ISBN Information

Print ISBN: 9780470518236

Online ISBN: 9780470699638

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Keywords:

  • biological matrices and chemical biomonitoring;
  • occupational and environmental chemical exposure assessment;
  • toxicogenomic application and risk assessment;
  • quantitative risk assessment process and low-dose extrapolation;
  • complex gene expression profile and toxicological pathways;
  • toxicogenomic biomarkers - potential uses;
  • toxicogenomic data and toxic tort litigation;
  • prior toxicogenomic biomarker validation

Summary

This chapter contains sections titled:

  • Introduction

  • Development and Application of Toxicogenomic Biomarkers

  • Toxicogenomics and the Identification of Interindividual Variability

  • Uses of Toxicogenomics in Occupational Health and Exposure Assessment

  • Applications of Toxicogenomics in Risk Assessment

  • Limitations and Potential Misuses of Toxicogenomic Biomarkers in Exposure Assessment

  • References