Chapter 9. Gene Expression Profiling of Transplacental Arsenic Carcinogenesis in Mice

  1. Saura C. Sahu
  1. Jie Liu1,
  2. Bhalchandra A. Diwan2,
  3. Raymond Tennant3 and
  4. Michael P. Waalkes1

Published Online: 14 OCT 2008

DOI: 10.1002/9780470699638.ch9

Toxicogenomics: A Powerful Tool for Toxicity Assessment

Toxicogenomics: A Powerful Tool for Toxicity Assessment

How to Cite

Liu, J., Diwan, B. A., Tennant, R. and Waalkes, M. P. (2008) Gene Expression Profiling of Transplacental Arsenic Carcinogenesis in Mice, in Toxicogenomics: A Powerful Tool for Toxicity Assessment (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470699638.ch9

Editor Information

  1. Division of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, Laurel, MD 20708, USA

Author Information

  1. 1

    Inorganic Carcinogenesis Section, Laboratory of Comparative Carcinogenesis, National Cancer Institute at NIEHS, Research Triangle Park, NC, USA

  2. 2

    Basic Research Program, SAIC-Frederick, Inc., NCI Frederick, MD, USA

  3. 3

    National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA

Publication History

  1. Published Online: 14 OCT 2008
  2. Published Print: 10 OCT 2008

ISBN Information

Print ISBN: 9780470518236

Online ISBN: 9780470699638

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Keywords:

  • real-time reverse transcriptase polymerase chain reaction (RT-PCR);
  • mice transplacental arsenic carcinogenesis;
  • transplacental arsenic carcinogenesis gene expression profiling;
  • aberrant estrogen signaling;
  • gene expression profiling and in utero arsenic exposure;
  • fetal lung gene expression;
  • cDNA microarray and bioinformatic expression analysis

Summary

This chapter contains sections titled:

  • Introduction

  • Materials and Methods

  • Results and Discussion

  • Summary

  • Acknowledgments

  • References