• Please log in or register to access this feature.

11. Solvent-Free Synthesis

  1. Wei Zhang3,
  2. Berkeley W. Cue Jr.4
  1. James Mack1,
  2. Sivaramakrishnan Muthukrishnan2

Published Online: 29 MAY 2012

DOI: 10.1002/9780470711828.ch11

Book Title

Green Techniques for Organic Synthesis and Medicinal Chemistry

Green Techniques for Organic Synthesis and Medicinal Chemistry

Additional Information

How to Cite

Mack, J. and Muthukrishnan, S. (2012) Solvent-Free Synthesis, in Green Techniques for Organic Synthesis and Medicinal Chemistry (eds W. Zhang and B. W. Cue), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470711828.ch11

Editor Information

  1. 3

    Center for Green Chemistry, Department of Chemistry, University of Massachusetts Boston, Boston, Massachusetts, USA

  2. 4

    BWC Pharma Consulting, LLC, Green Chemistry and Pharmaceutical Sciences, Ledyard, Connecticut, USA

Author Information

  1. 1

    University of Cincinnati, Cincinnati, Ohio, USA

  2. 2

    Strategic Innovation & Technology, Procter & Gamble Co., Cincinnati, Ohio, USA

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 22 JUN 2012

ISBN Information

Print ISBN: 9780470711514

Online ISBN: 9780470711828

SEARCH

CHAPTER TOOLS

Get PDF (825K)

Keywords:

  • solvent-free synthesis;
  • alternative methods to solution based synthesis;
  • planetary and vibratory mills, for solvent-free chemical reactions;
  • ball milling reactions in two-step, activation step and ignition step;
  • carbonyl based solvent-free reactions, using ball milling;
  • Sonogashira reaction, solvent-free high speed ball milling;
  • solvent-free ball milling conditions and “Click” chemistry

Summary

This chapter contains sections titled:

  • Introduction

  • Alternative Methods to Solution Based Synthesis

  • References

Get PDF (825K)