13. Ultrasonic Reactions

  1. Wei Zhang3 and
  2. Berkeley W. Cue Jr.4
  1. Rodrigo Cella1 and
  2. Hélio A. Stefani2

Published Online: 29 MAY 2012

DOI: 10.1002/9780470711828.ch13

Green Techniques for Organic Synthesis and Medicinal Chemistry

Green Techniques for Organic Synthesis and Medicinal Chemistry

How to Cite

Cella, R. and Stefani, H. A. (2012) Ultrasonic Reactions, in Green Techniques for Organic Synthesis and Medicinal Chemistry (eds W. Zhang and B. W. Cue), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470711828.ch13

Editor Information

  1. 3

    Center for Green Chemistry, Department of Chemistry, University of Massachusetts Boston, Boston, Massachusetts, USA

  2. 4

    BWC Pharma Consulting, LLC, Green Chemistry and Pharmaceutical Sciences, Ledyard, Connecticut, USA

Author Information

  1. 1

    Oxiteno Industry and Trade, Mauá, São Paulo, Brazil

  2. 2

    University of São Paulo, Faculty of Pharmaceutical Science, São Paulo, Brazil

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 22 JUN 2012

ISBN Information

Print ISBN: 9780470711514

Online ISBN: 9780470711828



  • ultrasonic reactions and green chemistry;
  • sonochemistry, ultrasound promoting chemical reactions;
  • cavitation effect on chemical reactions;
  • Knoevenagel condensation, for important intermediates;
  • heterocycles and new synthetic protocols;
  • highly functionalized heterocycles, regioselective;
  • Suzuki–Miyaura, Stille, Kumada, and Hiyama coupling;
  • ultrasound-assisted cross-coupling between organoltellurides;
  • synthetic organic reactions, circumventing environmental concerns


This chapter contains sections titled:

  • Introduction

  • How Does Cavitation Work?

  • Condensation Reactions

  • Michael Additions

  • Mannich Reactions

  • Heterocycles Synthesis

  • Coupling Reactions

  • Miscellaneous

  • Conclusions

  • References