17. The Role of Ionic Liquids in the Pharmaceutical Manufacturing Processes

  1. Wei Zhang2 and
  2. Berkeley W. Cue Jr.3
  1. Hui Wang,
  2. Xiaosi Zhou,
  3. Gabriela Gurau and
  4. Robin D. Rogers

Published Online: 29 MAY 2012

DOI: 10.1002/9780470711828.ch17

Green Techniques for Organic Synthesis and Medicinal Chemistry

Green Techniques for Organic Synthesis and Medicinal Chemistry

How to Cite

Wang, H., Zhou, X., Gurau, G. and Rogers, R. D. (2012) The Role of Ionic Liquids in the Pharmaceutical Manufacturing Processes, in Green Techniques for Organic Synthesis and Medicinal Chemistry (eds W. Zhang and B. W. Cue), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470711828.ch17

Editor Information

  1. 2

    Center for Green Chemistry, Department of Chemistry, University of Massachusetts Boston, Boston, Massachusetts, USA

  2. 3

    BWC Pharma Consulting, LLC, Green Chemistry and Pharmaceutical Sciences, Ledyard, Connecticut, USA

Author Information

  1. Center for Green Manufacturing and Department of Chemistry, The University of Alabama, Tuscaloosa, Alabama, USA

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 22 JUN 2012

ISBN Information

Print ISBN: 9780470711514

Online ISBN: 9780470711828

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Keywords:

  • ionic liquids in pharmaceutical processes, using modular IL strategy;
  • ILs as solvents, synthesis of drugs or drug intermediates;
  • ILs and biphasic systems with classic organic solvents;
  • application of ILs in polymorphic design of API, AD;
  • ILs in pharmaceutical separations, as chiral selectors in MEKC;
  • ILs, new opportunities to HSGC, for determining residual solvents;
  • ILs in drug extraction from natural products, using VOCs;
  • ILs, and their unique properties, as promising “green solvents”

Summary

This chapter contains sections titled:

  • Introduction

  • Finding the Right Role for ILs in the Pharmaceutical Industry

  • Conclusions and Prospects

  • References