6. Fluorous Catalysis

  1. Wei Zhang3 and
  2. Berkeley W. Cue Jr.4
  1. László T. Mika1 and
  2. István T. Horváth2

Published Online: 29 MAY 2012

DOI: 10.1002/9780470711828.ch6

Green Techniques for Organic Synthesis and Medicinal Chemistry

Green Techniques for Organic Synthesis and Medicinal Chemistry

How to Cite

Mika, L. T. and Horváth, I. T. (2012) Fluorous Catalysis, in Green Techniques for Organic Synthesis and Medicinal Chemistry (eds W. Zhang and B. W. Cue), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470711828.ch6

Editor Information

  1. 3

    Center for Green Chemistry, Department of Chemistry, University of Massachusetts Boston, Boston, Massachusetts, USA

  2. 4

    BWC Pharma Consulting, LLC, Green Chemistry and Pharmaceutical Sciences, Ledyard, Connecticut, USA

Author Information

  1. 1

    Institute of Chemistry, Eötvös University, Budapest, Hungary

  2. 2

    Department of Biology and Chemisry, City University of Hong Kong, Kowloon, Hong Kong

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 22 JUN 2012

ISBN Information

Print ISBN: 9780470711514

Online ISBN: 9780470711828



  • fluorous catalysis;
  • fluorous biphase reaction;
  • product/catalyst separation and SFLP catalysis;
  • temperature-dependent fluorous-solid/liquid biphase concept;
  • fluorous transition metal catalysts and ligands;
  • asymmetric hydrogenation, using prochiral substrates;
  • catalytic hydrosilylation, chemical transformation for silicon compounds;
  • Negishi coupling of arylzinc bromides, and fluorous Suzuki coupling;
  • phosphine-free palladium-catalyzed Heck reaction;
  • fluorous organocatalysis, Hajos–Parrish–Eder–Sauer–Wiechert reaction


This chapter contains sections titled:

  • Introduction and the Principles of Fluorous Catalysis

  • Ligands for Fluorous Transition Metal Catalysts

  • Synthetic Application of Fluorous Catalysis

  • Fluorous Organocatalysis

  • References