8. Biocatalysis

  1. Wei Zhang3 and
  2. Berkeley W. Cue Jr.4
  1. Qi Wu1 and
  2. Junhua Tao2

Published Online: 29 MAY 2012

DOI: 10.1002/9780470711828.ch8

Green Techniques for Organic Synthesis and Medicinal Chemistry

Green Techniques for Organic Synthesis and Medicinal Chemistry

How to Cite

Wu, Q. and Tao, J. (2012) Biocatalysis, in Green Techniques for Organic Synthesis and Medicinal Chemistry (eds W. Zhang and B. W. Cue), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470711828.ch8

Editor Information

  1. 3

    Center for Green Chemistry, Department of Chemistry, University of Massachusetts Boston, Boston, Massachusetts, USA

  2. 4

    BWC Pharma Consulting, LLC, Green Chemistry and Pharmaceutical Sciences, Ledyard, Connecticut, USA

Author Information

  1. 1

    Zhejiang University, Hangzhou, Zhejiang, China

  2. 2

    Metabomics Inc., Zhangjiagang, Jiangsu, China

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 22 JUN 2012

ISBN Information

Print ISBN: 9780470711514

Online ISBN: 9780470711828



  • biocatalysis;
  • 12 principles of GC, reducing environmental burden;
  • biocatalysis, biocatalysis toolboxes and synthetic applications;
  • “greener” and cost-effective, in small chiral molecule drug synthesis;
  • statin side chain precursor, chemoenzymatic synthesis;
  • chemical synthesis of semi-synthetic penicillins;
  • glycopeptide antibiotics, on industrial scale by biosynthesis;
  • chemoenzymatic green synthesis of paroxetine;
  • biocatalysis in pharmaceutical production, nascent stage


This chapter contains sections titled:

  • Introduction

  • Brief History of Biocatalysis

  • Biocatalysis Toolboxes

  • Enzymatic Synthesis of Pharmaceuticals

  • Summary

  • Acknowledgment

  • References