Chapter 15. The Role of Myeloperoxidase in the Microbicidal Activity of Polymorphonuclear Leukocytes

  1. David W. Fitzsimons
  1. S. J. Klebanoff,
  2. H. Rosen

Published Online: 27 MAY 2008

DOI: 10.1002/9780470715413.ch15

Book Title

Ciba Foundation Symposium 65 - Oxygen Free Radicals and Tissue Damage

Ciba Foundation Symposium 65 - Oxygen Free Radicals and Tissue Damage

Additional Information

How to Cite

Klebanoff, S. J. and Rosen, H. (2008) The Role of Myeloperoxidase in the Microbicidal Activity of Polymorphonuclear Leukocytes, in Ciba Foundation Symposium 65 - Oxygen Free Radicals and Tissue Damage (ed D. W. Fitzsimons), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470715413.ch15

Author Information

  1. Department of Medicine, University of Washington School of Medicine, Seattle, Washington

Publication History

  1. Published Online: 27 MAY 2008
  2. Published Print: 1 JAN 1979

ISBN Information

Print ISBN: 9780444900630

Online ISBN: 9780470715413

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Keywords:

  • myeloperoxidase;
  • phagosome;
  • polymorphonuclear leukocytes;
  • xanthine oxidase system;
  • antimicrobial system

Summary

This chapter contains section titled:

  • The MPO-Mediated Antimicrobial System

  • MPO-Independent Antimicrobial Systems

  • Formation of Hydroxyl Radicals

  • Formation of Singlet Oxygen

  • Conclusion

  • Acknowledgements

  • References

  • Discussion

  • Fertilization of Sea Urchin Eggs

  • References

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