Chapter 45. Mechanism of Histamine Release

  1. G. E. W. Wolstenholme O.B.E., M.A., M.B., B.Ch. and
  2. Cecilia M. O'Connor B.Sc.
  1. Georges Ungar

Published Online: 30 MAY 2008

DOI: 10.1002/9780470718957.ch45

Ciba Foundation Symposium - Histamine

Ciba Foundation Symposium - Histamine

How to Cite

Ungar, G. (1956) Mechanism of Histamine Release, in Ciba Foundation Symposium - Histamine (eds G. E. W. Wolstenholme and C. M. O'Connor), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470718957.ch45

Author Information

  1. Department of Pharmacology, U.S. Vitamin Corporation, Yonkers, New York

Publication History

  1. Published Online: 30 MAY 2008
  2. Published Print: 1 JAN 1956

ISBN Information

Print ISBN: 9780470722381

Online ISBN: 9780470718957



  • histamine release;
  • animal cells;
  • sub-cellular particles;
  • protein breakdown;
  • proteolytic activity


This Chapter Contains Section Title:

  • 1. Stimuli which are known to release histamine induce the appearance of protease activity in tissues and serum

  • 2. There is a quantitative correlation between protein breakdown and histamine release

  • 3. When proteolysis is inhibited, histamine fails to be released

  • References

  • Discussion

  • General Discussion