Chapter 16. Transfusion-Induced Polycythaemia as a Model for Studying Factors Influencing Erythropolesis

  1. G. E. W. Wolstenholme O.B.E., M.A., M.B., M.R.C.P. and
  2. Maeve O'Connor B.A.
  1. L. O. Jacobson,
  2. E. Goldwasser and
  3. C. W. Gurney

Published Online: 30 MAY 2008

DOI: 10.1002/9780470719190.ch16

Ciba Foundation Symposium - Haemopoiesis: Cell Production and its Regulation

Ciba Foundation Symposium - Haemopoiesis: Cell Production and its Regulation

How to Cite

Jacobson, L. O., Goldwasser, E. and Gurney, C. W. (1960) Transfusion-Induced Polycythaemia as a Model for Studying Factors Influencing Erythropolesis, in Ciba Foundation Symposium - Haemopoiesis: Cell Production and its Regulation (eds G. E. W. Wolstenholme and M. O'Connor), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470719190.ch16

Author Information

  1. Argonne Cancer Research Hospital, and the Departments of Medicine and Biochemistry, University of Chicago, Chicago

Publication History

  1. Published Online: 30 MAY 2008
  2. Published Print: 1 JAN 1960

ISBN Information

Print ISBN: 9780470722633

Online ISBN: 9780470719190

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Keywords:

  • haematopoietic system;
  • erythropoiesis;
  • normal rodents;
  • haemoglobin;
  • reticulocyte

Summary

The prelims comprise:

  • The Influence of Hypophysectomy on Erythropoiesis

  • Preparation and Methods of Use of the Polycythaemic Mouse for Erythropoietin Assay

  • Some Studies Using the Transfirsion-Induced Polycythaemic Mouse

  • A. The effect of Continued Polycythaemia on the Capacity to Re-Initiate Erythropoiesis

  • B. Transplantation of Polycythaemic Marrow

  • C. The Effect of an Atmosphere Containing 10 Percent Oxygen on the Erythropoietic Response of Polycythaemic Mice

  • D. The Effect of Cobaltous Chloride on Erythropoiesis in the Polycythaemic Mouse

  • The Response of Polycythaemic Irradiated Mice to Rat Bone Marrow

  • Establishment of a Unit of Erythropoietin

  • Site of Action of Erythropoietin

  • Summary and Conclusions

  • Reference

  • Discussion

  • General Discussion