Chapter 17. The Influence of HL-A Compatibility on the Fate of Corneal Grafts

  1. Ruth Porter and
  2. Julie Knight
  1. D. C. Gibbs,
  2. J. R. Batchelor and
  3. T. A. Casey

Published Online: 30 MAY 2008

DOI: 10.1002/9780470719985.ch17

Ciba Foundation Symposium 15 - Corneal Graft Failure

Ciba Foundation Symposium 15 - Corneal Graft Failure

How to Cite

Gibbs, D. C., Batchelor, J. R. and Casey, T. A. (1973) The Influence of HL-A Compatibility on the Fate of Corneal Grafts, in Ciba Foundation Symposium 15 - Corneal Graft Failure (eds R. Porter and J. Knight), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470719985.ch17

Author Information

  1. McIndoe Memorial Research Unit, Blond Laboratories, and the Corneo-Plastic Unit and Regional Eye Bank, Queen Victoria Hospital, East Grinstead

Publication History

  1. Published Online: 30 MAY 2008
  2. Published Print: 1 JAN 1973

ISBN Information

Print ISBN: 9789021940168

Online ISBN: 9780470719985

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Keywords:

  • allogeneic skin;
  • corneal grafts;
  • kidney grafts;
  • graft rejection;
  • autosomal genes

Summary

A retrospective study of HL-A antigen incompatibility between recipient and donor has been made in 100 cases of full-thickness corneal grafting. No clear-cut overall correlation between the clinical fate of the graft and HL-A incompatibility was observed, but there was an indication that in grafts transplanted to vascularized corneas, greater HL-A incompatibility was associated with a higher risk of rejection.