Chapter 11. Starling's Law of the Heart and the Geometry of the Ventricle

  1. Ruth Porter and
  2. David W. Fitzsimons
  1. I. T. Gabe

Published Online: 30 MAY 2008

DOI: 10.1002/9780470720066.ch11

Ciba Foundation Symposium 24 - Physiological Basis of Starling's Law of the Heart

Ciba Foundation Symposium 24 - Physiological Basis of Starling's Law of the Heart

How to Cite

Gabe, I. T. (1974) Starling's Law of the Heart and the Geometry of the Ventricle, in Ciba Foundation Symposium 24 - Physiological Basis of Starling's Law of the Heart (eds R. Porter and D. W. Fitzsimons), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470720066.ch11

Author Information

  1. Midhurst Medical Research Institute, Midhurst, Sussex

Publication History

  1. Published Online: 30 MAY 2008
  2. Published Print: 1 JAN 1974

ISBN Information

Print ISBN: 9789021940250

Online ISBN: 9780470720066

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Keywords:

  • starling's law;
  • heart;
  • geometry;
  • ventricle;
  • cardiac muscle

Summary

The change in force produced when the initial length of a cardiac muscle fibre is altered is the main basis of Starling's law of the heart. The effect of the geometry of the heart itself, in the absence of the muscle length-tension property, is explored theoretically by consideration of one- and two-dimensional models of the heart. In the one-dimensional model, flow and pressure are unchanged. In the two-dimensional model there is a small Starling law type of effect over a small working range, but as tension increases further, flow slightly diminishes for the same pressures produced. In the absence of the length-tension relation, equilibrium would not be achieved.