Chapter 4. Signs of Plasticity and Reconnection in Spinal Cord Damage

  1. Ruth Porter and
  2. David W. Fitzsimons
  1. P. D. Wall

Published Online: 30 MAY 2008

DOI: 10.1002/9780470720165.ch4

Ciba Foundation Symposium 34 - Outcome of Severe Damage to the Central Nervous System

Ciba Foundation Symposium 34 - Outcome of Severe Damage to the Central Nervous System

How to Cite

Wall, P. D. (1975) Signs of Plasticity and Reconnection in Spinal Cord Damage, in Ciba Foundation Symposium 34 - Outcome of Severe Damage to the Central Nervous System (eds R. Porter and D. W. Fitzsimons), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470720165.ch4

Author Information

  1. Cerebral Functions Research Group, Department of Anatomy, University College London

Publication History

  1. Published Online: 30 MAY 2008
  2. Published Print: 1 JAN 1975

ISBN Information

Print ISBN: 9789021940380

Online ISBN: 9780470720165

SEARCH

Keywords:

  • thalamus;
  • spinal cord damage;
  • plasticity;
  • dorsal column nuclei;
  • amphibia

Summary

Experiments on the thalamus, dorsal column nuclei and spinal cord in the adult cat and rat show that partial destruction of afferents to these regions leads to the immediate unmasking of certain types of activity which are normally inhibited. Chronic studies show that some cells begin to respond to afferent nerve impulses after a period in which the cell seems to have lost all inputs. Sprouting of terminals from remaining areas is one possible explanation for these late changes but one must also consider the possibility that the new connections result from axons which were already present but which normally were ineffective.