Chapter 17. The Role of Altered Lactate Kinetics in the Pathogenesis of Type B Lactic Acidosis

  1. Ruth Porter and
  2. Geralyn Lawrenson
  1. H. F. Woods1,
  2. H. Connor2 and
  3. G. T. Tucker1

Published Online: 30 MAY 2008

DOI: 10.1002/9780470720691.ch17

Ciba Foundation Symposium 87 - Metabolic Acidosis

Ciba Foundation Symposium 87 - Metabolic Acidosis

How to Cite

Woods, H. F., Connor, H. and Tucker, G. T. (1982) The Role of Altered Lactate Kinetics in the Pathogenesis of Type B Lactic Acidosis, in Ciba Foundation Symposium 87 - Metabolic Acidosis (eds R. Porter and G. Lawrenson), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470720691.ch17

Author Information

  1. 1

    University Department of Therapeutics, The Royal Hallamshire Hospital, Glossop Road, Shefieid SIO 2JF, UK

  2. 2

    County Hospital, Union Walk, Hereford HR1 2ER, UK

Publication History

  1. Published Online: 30 MAY 2008
  2. Published Print: 1 JAN 1982

ISBN Information

Print ISBN: 9780272796511

Online ISBN: 9780470720691

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Keywords:

  • metabolic acidosis;
  • lactate accumulation;
  • metabolic acidosis;
  • anaerobic metabolism;
  • glycolytic flux

Summary

This chapter contains section titled:

  • The Elevation of Blood Lactate Concentration

  • The Time-Course of Attainment of a New Steady-State Lactate Concentration

  • The Effect of Cessation of Hepatic Lactate Clearance on the Steady-State Lactate Concentration

  • The Control of Hepatic Lactate Uptake by Blood Flow Through the Liver

  • General Conclusions

  • Reference

  • Discussion

  • Reference