Chapter 7. The Turnover and Degradation of Collagen

  1. David Evered and
  2. Julie Whelan
  1. Stephen M. Krane

Published Online: 30 MAY 2008

DOI: 10.1002/9780470720950.ch7

Ciba Foundation Symposium 114 - Fibrosis

Ciba Foundation Symposium 114 - Fibrosis

How to Cite

Krane, S. M. (1985) The Turnover and Degradation of Collagen, in Ciba Foundation Symposium 114 - Fibrosis (eds D. Evered and J. Whelan), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470720950.ch7

Author Information

  1. Department of Medicine, Harvard Medical School and the Medical Services (Arthritis Unit), Massachusetts General Hospital, Boston, Massachusetts 02114, USA

Publication History

  1. Published Online: 30 MAY 2008
  2. Published Print: 1 JAN 1985

ISBN Information

Print ISBN: 9780272798140

Online ISBN: 9780470720950

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Keywords:

  • degradation of collagen;
  • interstitial collagens;
  • cross-links in the fibril;
  • regulation of collagenolysis;
  • latent collagenase

Summary

This chapter contains section titled:

  • Biosynthesis and Secretion of Collagenase

  • Activation of latent collagenase

  • Interaction of Active Enzyme with Extracellular Collagen Substrate

  • Influence of Inhibition of Enzyme Activity

  • Concluding Comments

  • Acknowledgements

  • References

  • Discussion

  • References