Chapter 1. Concepts

  1. Jonathan W. Steed B.Sc., Ph.D. Professor Lecturer Associate Editor Recipient1 and
  2. Jerry L. Atwood B.S., Ph.D. Assistant Professor Associate Professor Professor2

Published Online: 26 JAN 2009

DOI: 10.1002/9780470740880.ch1

Supramolecular Chemistry, Second Edition

Supramolecular Chemistry, Second Edition

How to Cite

Steed, J. W. and Atwood, J. L. (2009) Concepts, in Supramolecular Chemistry, Second Edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470740880.ch1

Author Information

  1. 1

    Department of Chemistry, Durham University, UK

  2. 2

    Department of Chemistry, University of Missouri, Columbia, USA

Publication History

  1. Published Online: 26 JAN 2009
  2. Published Print: 9 JAN 2009

ISBN Information

Print ISBN: 9780470512333

Online ISBN: 9780470740880



  • supramolecular chemistry - ‘chemistry of molecular assemblies and intermolecular bond’;
  • supramolecular host–guest chemistry and host–guest complex;
  • solvent of binding constant;
  • cooperativity and chelate effect;
  • supramolecular host design and preorganisation and complementarity;
  • chelate complexes in solution - thermodynamic, kinetic selectivity, and discrimination;
  • solvation and hydrophobic effects;
  • chelate macrocyclic effects and complementarity concept;
  • supramolecular chemistry timeline


This chapter contains sections titled:

  • Definition and Development of Supramolecular Chemistry

  • Classification of Supramolecular Host–Guest Compounds

  • Receptors, Coordination and the Lock and Key Analogy

  • Binding Constants

  • Cooperativity and the Chelate Effect

  • Preorganisation and Complementarity

  • Thermodynamic and Kinetic Selectivity, and Discrimination

  • Nature of Supramolecular Interactions

  • Solvation and Hydrophobic Effects

  • Supramolecular Concepts and Design

  • Summary

  • Study Problems

  • Suggested Further Reading

  • References