Chapter 1. The Basics of Protein Sequence Analysis
- Janusz M. Bujnicki1,2
Published Online: 18 DEC 2008
DOI: 10.1002/9780470741894.ch1
Copyright © 2009 John Wiley & Sons, Ltd
Book Title
Prediction of Protein Structures, Functions, and Interactions
Additional Information
How to Cite
Kaminska, K. H., Milanowska, K. and Bujnicki, J. M. (2008) The Basics of Protein Sequence Analysis, in Prediction of Protein Structures, Functions, and Interactions (ed J. M. Bujnicki), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470741894.ch1
Editor Information
- 1
Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland
- 2
Laboratory of Bioinformatics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, ul. Umultowska 89, 61-614 Poznan, Poland
Publication History
- Published Online: 18 DEC 2008
- Published Print: 19 DEC 2008
ISBN Information
Print ISBN: 9780470517673
Online ISBN: 9780470741894
- Summary
- Chapter
Keywords:
- protein sequence analysis basics;
- protein-encoding genes and duplications;
- domains - protein sequence primary functional units;
- gene fragment encoding domains;
- protein families databases - domains and motifs;
- database searches and pairwise alignments;
- sequence alignment - global Needleman-Wunsch and local Smith-Waterman;
- multiple sequence alignment;
- domain prediction
Summary
This chapter contains sections titled:
Introduction
Domains: Primary Functional Units in Protein Sequence
Sequence Motifs
Databases of Protein Families, Domains, and Motifs
Database Searches and Pairwise Alignments
Sequence Clustering
Multiple Sequence Alignment
Relationship of Multiple Sequence Alignments to Phylogenetic Analysis
Prediction of Domains
Summary
Acknowledgements
References