Chapter 10. Protein Function Prediction via Analysis of Interactomes

  1. Janusz M. Bujnicki2,3
  1. Elena Nabieva and
  2. Mona Singh

Published Online: 18 DEC 2008

DOI: 10.1002/9780470741894.ch10

Prediction of Protein Structures, Functions, and Interactions

Prediction of Protein Structures, Functions, and Interactions

How to Cite

Nabieva, E. and Singh, M. (2008) Protein Function Prediction via Analysis of Interactomes, in Prediction of Protein Structures, Functions, and Interactions (ed J. M. Bujnicki), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470741894.ch10

Editor Information

  1. 2

    Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland

  2. 3

    Laboratory of Bioinformatics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, ul. Umultowska 89, 61-614 Poznan, Poland

Author Information

  1. Department of Computer Science & Lewis-Sigler Institute for Integrative Genomics, Carl Icahn Laboratory, Princeton University, Princeton, NJ 08544, USA

Publication History

  1. Published Online: 18 DEC 2008
  2. Published Print: 19 DEC 2008

ISBN Information

Print ISBN: 9780470517673

Online ISBN: 9780470741894

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Keywords:

  • genome sequencing efforts;
  • protein function prediction via interactome analysis;
  • network visualization software;
  • cut-based methods and functional annotation;
  • network-based clustering;
  • network alignments and biological networks;
  • multiple predictions and multiple annotations;
  • high-throughput techniques in protein physical interaction

Summary

This chapter contains sections titled:

  • Introduction

  • Further Background

  • Incorporating Interaction Reliability

  • Algorithms

  • Assessment of Prediction Quality

  • Conclusions

  • Acknowledgments

  • References