Chapter 4. Template Based Prediction of Three-Dimensional Protein Structures: Fold Recognition and Comparative Modeling

  1. Janusz M. Bujnicki1,2
  1. Jan Kosiński1,
  2. Karolina L. Tkaczuk1,
  3. Joanna M. Kasprzak2 and
  4. Janusz M. Bujnicki1,2

Published Online: 18 DEC 2008

DOI: 10.1002/9780470741894.ch4

Prediction of Protein Structures, Functions, and Interactions

Prediction of Protein Structures, Functions, and Interactions

How to Cite

Kosiński, J., Tkaczuk, K. L., Kasprzak, J. M. and Bujnicki, J. M. (2008) Template Based Prediction of Three-Dimensional Protein Structures: Fold Recognition and Comparative Modeling, in Prediction of Protein Structures, Functions, and Interactions (ed J. M. Bujnicki), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470741894.ch4

Editor Information

  1. 1

    Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland

  2. 2

    Laboratory of Bioinformatics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, ul. Umultowska 89, 61-614 Poznan, Poland

Author Information

  1. 1

    Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland

  2. 2

    Laboratory of Bioinformatics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, ul. Umultowska 89, 61-614 Poznan, Poland

Publication History

  1. Published Online: 18 DEC 2008
  2. Published Print: 19 DEC 2008

ISBN Information

Print ISBN: 9780470517673

Online ISBN: 9780470741894

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Keywords:

  • 3D protein structures - template based prediction;
  • comparative modeling;
  • sequence profiles and intermediate sequence search method (ISS) strategy;
  • Model Quality Assessment Programs (MQAPs);
  • model building methods;
  • rigid body assembly methods;
  • database search methods and loops;
  • Model quality assessment (MQA);
  • protein structure modeling and function prediction

Summary

This chapter contains sections titled:

  • Introduction

  • Steps of Comparative Modeling

  • Accuracy of Comparative Models

  • Protein Structure Modeling and Function Prediction

  • Acknowledgements

  • References