Chapter 6. Quality Assessment of Protein Models

  1. Janusz M. Bujnicki2,3
  1. Björn Wallner and
  2. Arne Elofsson

Published Online: 18 DEC 2008

DOI: 10.1002/9780470741894.ch6

Prediction of Protein Structures, Functions, and Interactions

Prediction of Protein Structures, Functions, and Interactions

How to Cite

Wallner, B. and Elofsson, A. (2008) Quality Assessment of Protein Models, in Prediction of Protein Structures, Functions, and Interactions (ed J. M. Bujnicki), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470741894.ch6

Editor Information

  1. 2

    Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland

  2. 3

    Laboratory of Bioinformatics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, ul. Umultowska 89, 61-614 Poznan, Poland

Author Information

  1. Center for Biomembrane Research and Stockholm Bioinformatics Center, Stockholm University, SE-106 91 Stockholm, Sweden

Publication History

  1. Published Online: 18 DEC 2008
  2. Published Print: 19 DEC 2008

ISBN Information

Print ISBN: 9780470517673

Online ISBN: 9780470741894



  • Model Quality Assessment programs (MQAPs);
  • protein model quality assessment;
  • MQAPs and quality of model prediction;
  • ProQres, ProQprof and ProQlocal;
  • consensus analysis and Pconslocal method;
  • Receiver Operating Characteristic curves (ROC);
  • global quality assessment;
  • Best Global MQAP;
  • MQAPs and future improvements


This chapter contains sections titled:

  • Introduction

  • Short Historical Overview

  • MQAPs Developed to Predict Quality of Models

  • Local versus Global Predictors

  • Performance in CASP7

  • Discussion

  • Acknowledgments

  • References