Pathological Techniques in Toxicology
Published Online: 15 DEC 2009
Copyright © 2009 John Wiley & Sons, Ltd. All rights reserved.
General, Applied and Systems Toxicology
How to Cite
Greaves, P. 2009. Pathological Techniques in Toxicology. General, Applied and Systems Toxicology. .
- Published Online: 15 DEC 2009
Histopathological evaluation remains an important part of the assessment of the adverse effects of xenobiotics on the whole organism. In addition to conventional special staining techniques and electron microscopy, new techniques involving immunocytochemistry, molecular biology and novel visualization procedures have provided additional objective techniques that have enabled better functional and morphological characterization of induced alterations in organs of the body. This chapter covers both conventional and new methods involved in the microscopical assessment of tissue changes induced by xenobiotics.
- histological stains;
- light microscopic techniques;
- electron microscopy;
- molecular techniques