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Nanotoxicology—The Toxicology of Nanomaterials

Toxicology of Specific Groups of Substances

  1. Kristin Gellein PhD,
  2. Tore Syversen Msc, Dr Philos

Published Online: 15 DEC 2009

DOI: 10.1002/9780470744307.gat044

General, Applied and Systems Toxicology

General, Applied and Systems Toxicology

How to Cite

Gellein, K. and Syversen, T. 2009. Nanotoxicology—The Toxicology of Nanomaterials. General, Applied and Systems Toxicology. .

Author Information

  1. Norwegian University of Science and Technology, Department of Neuroscience, Faculty of Medicine, Trondheim, Norway

Publication History

  1. Published Online: 15 DEC 2009


Nanotoxicology is a new and fast-growing discipline that deals with the interaction between engineered nanostructures and biological systems. Because of their size, these materials have unusual physicochemical properties that make them different from bulk materials of the same chemical composition. However, the same properties that make these materials very attractive in a range of technological applications, also raise concern about adverse effects in biological systems. Today, a limited amount of data is available on possible effects on man and the environment. Nanomaterials (NMs) are currently available in a wide variety of compositions, and traditional approaches of toxicity testing are often not directly applicable. Studies so far, both in vivo and in vitro, indicate that these materials have the potential to cause adverse effects. As both the production volume and application range of NMs expands rapidly there is an urgent need to develop adequate toxicity testing and evaluation of these products.


  • nanotoxicology;
  • nanomaterials