Susceptibility of Children to Environmental Xenobiotics
Environmental and Ecotoxicology
Published Online: 15 DEC 2009
Copyright © 2009 John Wiley & Sons, Ltd. All rights reserved.
General, Applied and Systems Toxicology
How to Cite
Woolf, A. D. and Sandel, M. 2009. Susceptibility of Children to Environmental Xenobiotics. General, Applied and Systems Toxicology. .
- Published Online: 15 DEC 2009
The growth of interest in paediatric environmental health reflects a widespread recognition that the impact of the environment on children's health is of major importance for this and succeeding generations. Children have a greater vulnerability to the adverse health effects of many environmental toxicants and xenobiotics than do adults, by virtue of their smaller size, increased weight-adjusted intake of toxicants, developmental differences in body systems and functions, overall physiological and toxicodynamic differences, and differences in the environments they inhabit, the air they breathe, the foods they eat and the behaviours they display every day. The overall impact of such adverse effects of the environment, manifested by subsequent poorer health and the need for costly healthcare services, is amplified by the longer lifespans of children and is associated with intergenerational transmission of harmful effects, to the detriment of mankind. Conversely there is also great potential for averting such harmful effects by improving the quality of the environment and sparing children the consequences of such exposures.
- children's environmental health;
- paediatric environmental health;
- children's hazards