12. Pulmonary Endothelium and Vasomotor Control

  1. Norbert F. Voelkel2 and
  2. Sharon Rounds Chief3,4
  1. Nikki L. Jernigan,
  2. Benjimen R. Walker and
  3. Thomas C. Resta

Published Online: 11 SEP 2009

DOI: 10.1002/9780470747490.ch12

The Pulmonary Endothelium: Function in health and disease

The Pulmonary Endothelium: Function in health and disease

How to Cite

Jernigan, N. L., Walker, B. R. and Resta, T. C. (2009) Pulmonary Endothelium and Vasomotor Control, in The Pulmonary Endothelium: Function in health and disease (eds N. F. Voelkel and S. Rounds), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470747490.ch12

Editor Information

  1. 2

    The E. Raymond Fenton Professor of Pulmonary Research, Director, Victoria Johnson Center for Pulmonary Obstructive Disease Research, Pulmonary and Critical Care Medicine Division, Virginia Commonwealth University, Richmond, VA 23298, USA

  2. 3

    Alpert Medical School of Brown University, Medical Service, Providence VA, USA

  3. 4

    Medical Center, Providence, RI 02908, USA

Author Information

  1. Department of Cell Biology and Physiology, Vascular Physiology Group, University of New Mexico Health Sciences Center, Albuquerque, NM, USA

Publication History

  1. Published Online: 11 SEP 2009
  2. Published Print: 16 OCT 2009

ISBN Information

Print ISBN: 9780470723616

Online ISBN: 9780470747490



  • pulmonary endothelium and vasomotor control;
  • endothelium from vascular bed - endothelial cell (EC) heterogeneity;
  • endothelial dysfunction between vasoconstrictors and vasodilators;
  • vasoactive substances;
  • pulmonary vascular tone regulation by endothelium;
  • arachidonic acid (AA);
  • arachidonic acid metabolites;
  • lipoxygenase pathway;
  • endothelial ion channels and membrane potential;
  • endothelium - pulmonary vascular tone regulator


This chapter contains sections titled:

  • Introduction

  • Generation, Metabolism, and Degradation of Vasoactive Substances

  • Endothelial Ion Channels, Membrane Potential, and Regulation of Calcium Entry

  • Conclusions and Perspectives

  • References