28. Collagen Vascular Diseases and Pulmonary Endothelium

  1. Norbert F. Voelkel4 and
  2. Sharon Rounds Chief5,6
  1. Pradeep R. Raioc1 and
  2. Carlyne D. Cool2,3

Published Online: 11 SEP 2009

DOI: 10.1002/9780470747490.ch28

The Pulmonary Endothelium: Function in health and disease

The Pulmonary Endothelium: Function in health and disease

How to Cite

Raioc, P. R. and Cool, C. D. (2009) Collagen Vascular Diseases and Pulmonary Endothelium, in The Pulmonary Endothelium: Function in health and disease (eds N. F. Voelkel and S. Rounds), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470747490.ch28

Editor Information

  1. 4

    The E. Raymond Fenton Professor of Pulmonary Research, Director, Victoria Johnson Center for Pulmonary Obstructive Disease Research, Pulmonary and Critical Care Medicine Division, Virginia Commonwealth University, Richmond, VA 23298, USA

  2. 5

    Alpert Medical School of Brown University, Medical Service, Providence VA, USA

  3. 6

    Medical Center, Providence, RI 02908, USA

Author Information

  1. 1

    Division of Pulmonary and Critical Care Medicine, University of Colorado Health Sciences Center, Denver, CO, USA

  2. 2

    Department of Pathology, National Jewish Health, Denver, CO, USA

  3. 3

    Department of Pathology, University of Colorado Health Sciences Center, Aurora, CO, USA

Publication History

  1. Published Online: 11 SEP 2009
  2. Published Print: 16 OCT 2009

ISBN Information

Print ISBN: 9780470723616

Online ISBN: 9780470747490

SEARCH

Keywords:

  • collagen vascular diseases and pulmonary endothelium;
  • systemic sclerosis (SSc) or scleroderma and affecting endothelium;
  • mixed connective tissue disease (MCTD);
  • pulmonary arterial hypertension (PAH);
  • immune dysfunction feature of scleroderma;
  • apoptosis and collagen vascular diseases;
  • SSc and defective endothelial-dependent vasodilation;
  • circulating EC progenitors (CEPs);
  • ECs in PAH and decreased prostacyclin synthase levels in autoimmune and idiopathic disease

Summary

This chapter contains sections titled:

  • Introduction

  • Mechanisms of Endothelial Cell Injury in Collagen Vascular Disease-Associated PAH

  • Mediators of Endothelial Dysfunction in Collagen Vascular Diseases

  • Circulating EC in Collagen Vascular Disease

  • Conclusions and Perspectives

  • References