4. Pulmonary Endothelial Cell Interactions with the Extracellular Matrix

  1. Norbert F. Voelkel2 and
  2. Sharon Rounds Chief3,4
  1. Katie L. Grinnell and
  2. Elizabeth O. Harrington

Published Online: 11 SEP 2009

DOI: 10.1002/9780470747490.ch4

The Pulmonary Endothelium: Function in health and disease

The Pulmonary Endothelium: Function in health and disease

How to Cite

Grinnell, K. L. and Harrington, E. O. (2009) Pulmonary Endothelial Cell Interactions with the Extracellular Matrix, in The Pulmonary Endothelium: Function in health and disease (eds N. F. Voelkel and S. Rounds), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470747490.ch4

Editor Information

  1. 2

    The E. Raymond Fenton Professor of Pulmonary Research, Director, Victoria Johnson Center for Pulmonary Obstructive Disease Research, Pulmonary and Critical Care Medicine Division, Virginia Commonwealth University, Richmond, VA 23298, USA

  2. 3

    Alpert Medical School of Brown University, Medical Service, Providence VA, USA

  3. 4

    Medical Center, Providence, RI 02908, USA

Author Information

  1. Vascular Research Laboratory, Providence VA Medical Center, Alpert Medical School of Brown University, Providence, RI 02908, USA

Publication History

  1. Published Online: 11 SEP 2009
  2. Published Print: 16 OCT 2009

ISBN Information

Print ISBN: 9780470723616

Online ISBN: 9780470747490

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Keywords:

  • pulmonary endothelial cell interactions and extracellular matrix;
  • CELL–ECM interactions;
  • ECM remodeling;
  • focal adhesions/focal contacts/fibrillar adhesions;
  • signaling molecules associated with CELL–ECM structures;
  • final cell–ECM adhesion complex;
  • pulmonary endothelial barrier function;
  • EC–ECM interaction in pulmonary vasculature;
  • EC–ECM lung tissue arrangement

Summary

This chapter contains sections titled:

  • Components of Cell–ECM Interactions

  • Functional Effect of EC–ECM Interactions in the Pulmonary Vasculature

  • Conclusions and Perspectives

  • References