5. Pulmonary Endothelial Cell Calcium Signaling and Regulation of Lung Vascular Barrier Function

  1. Norbert F. Voelkel2 and
  2. Sharon Rounds Chief3,4
  1. Nebojsa Knezevic,
  2. Mohammad Tauseef and
  3. Dolly Mehta

Published Online: 11 SEP 2009

DOI: 10.1002/9780470747490.ch5

The Pulmonary Endothelium: Function in health and disease

The Pulmonary Endothelium: Function in health and disease

How to Cite

Knezevic, N., Tauseef, M. and Mehta, D. (2009) Pulmonary Endothelial Cell Calcium Signaling and Regulation of Lung Vascular Barrier Function, in The Pulmonary Endothelium: Function in health and disease (eds N. F. Voelkel and S. Rounds), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470747490.ch5

Editor Information

  1. 2

    The E. Raymond Fenton Professor of Pulmonary Research, Director, Victoria Johnson Center for Pulmonary Obstructive Disease Research, Pulmonary and Critical Care Medicine Division, Virginia Commonwealth University, Richmond, VA 23298, USA

  2. 3

    Alpert Medical School of Brown University, Medical Service, Providence VA, USA

  3. 4

    Medical Center, Providence, RI 02908, USA

Author Information

  1. Center for Lung and Vascular Biology, Department of Pharmacology, University of Illinois at Chicago, Chicago, IL, USA

Publication History

  1. Published Online: 11 SEP 2009
  2. Published Print: 16 OCT 2009

ISBN Information

Print ISBN: 9780470723616

Online ISBN: 9780470747490

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Keywords:

  • pulmonary endothelial cell calcium signaling;
  • Ryanodine receptors;
  • TRP channel expression in ECs;
  • calcium signaling and endothelial barrier function;
  • intracellular signaling mechanisms and endothelial permeability regulation;
  • segmental variation of endothelial permeability;
  • endothelial handling of ions;
  • Ca2+ - key second messenger

Summary

This chapter contains sections titled:

  • Introduction

  • Calcium Response

  • Calcium Signaling and Endothelial Barrier Function

  • Endothelial Handling of Other Ions

  • Conclusions and Perspectives

  • References