Chapter 1. Characterization of Nanomaterials for Toxicological Evaluation

  1. Saura C. Sahu3 and
  2. Daniel A. Casciano4
  1. Kevin W. Powers1,
  2. Maria Palazuelos1,
  3. Scott C. Brown1 and
  4. Stephen M. Roberts2

Published Online: 18 AUG 2009

DOI: 10.1002/9780470747803.ch1



How to Cite

Powers, K. W., Palazuelos, M., Brown, S. C. and Roberts, S. M. (2009) Characterization of Nanomaterials for Toxicological Evaluation, in Nanotoxicity (eds S. C. Sahu and D. A. Casciano), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470747803.ch1

Editor Information

  1. 3

    Division of Toxicology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, 8301 Muirkirk Road, Laurel, MD 20708, USA

  2. 4

    Department for Applied Science, University of Arkansas at Little Rock, Little Rock, AR, USA

Author Information

  1. 1

    Particle Engineering Research Center, University of Florida, Gainesville, FL 32611, USA

  2. 2

    CEHT, University of Florida, Box 110885, Gainesville, FL 32611, USA

Publication History

  1. Published Online: 18 AUG 2009
  2. Published Print: 21 AUG 2009

ISBN Information

Print ISBN: 9780470741375

Online ISBN: 9780470747803



  • nanostructured materials (NSMs) proper characterization in toxicological evaluation;
  • quantifying NSM size, shape and agglomerate structure;
  • NSMs and scanning electronmicroscopy (SEM), TEM and AFM;
  • Nanoparticle Information Library (NIL);
  • NSM sampling characterization and powder technology;
  • sampling variability and bulk heterogeneity increase;
  • particle size and toxicity importance;
  • particle shape and toxicity;
  • NSMs dispersed in liquid measurement and centrifugal sedimentation;
  • understanding NSMs properties and toxicity mechanism determination


This chapter contains sections titled:

  • Introduction

  • Gathering Existing Data

  • Sampling

  • Particle Size Distribution

  • Particle Shape

  • State of Dispersion

  • Surface Properties

  • Recommended

  • Conclusions

  • References