Chapter 16. In Vitro and In Vivo Toxicity Study of Nanoparticles

  1. Saura C. Sahu3 and
  2. Daniel A. Casciano4
  1. Jayoung Jeong1,
  2. Wan-Seob Cho2,
  3. Seung Hee Kim1 and
  4. Myung-Haing Cho2

Published Online: 18 AUG 2009

DOI: 10.1002/9780470747803.ch16

Nanotoxicity

Nanotoxicity

How to Cite

Jeong, J., Cho, W.-S., Kim, S. H. and Cho, M.-H. (2009) In Vitro and In Vivo Toxicity Study of Nanoparticles, in Nanotoxicity (eds S. C. Sahu and D. A. Casciano), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470747803.ch16

Editor Information

  1. 3

    Division of Toxicology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, 8301 Muirkirk Road, Laurel, MD 20708, USA

  2. 4

    Department for Applied Science, University of Arkansas at Little Rock, Little Rock, AR, USA

Author Information

  1. 1

    Division of Toxicological Research, National Institute of Toxicological Research, Korea Food & Drug Administration, Seoul 122–704, Korea

  2. 2

    Division of Toxicological Research, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Korea

Publication History

  1. Published Online: 18 AUG 2009
  2. Published Print: 21 AUG 2009

ISBN Information

Print ISBN: 9780470741375

Online ISBN: 9780470747803

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Keywords:

  • in vitro and in vivo nanoparticle toxicity study;
  • nanoparticle sterility and nano-safety;
  • in vitro mechanistic toxicology of nanoparticles;
  • interactions between nanoparticles and heparin-treated blood;
  • in vitro toxicity assays and safe nanotechnology implementation;
  • monitoring apoptosis in human hepatocarcinoma cells treated with nanoparticles;
  • acute toxicity and evaluating nanoparticle toxic characteristics;
  • nanoparticles entrapped by reticuloendothelial system (RES);
  • nanomaterial ability to traverse skin and dermatotoxic potential;
  • UV irradiation, tape-stripping, abrasion and penetration efficacy

Summary

This chapter contains sections titled:

  • In Vitro Toxicity Study of Nanoparticles

  • In Vivo Toxicity Study of Nanoparticles

  • Acknowledgement

  • References